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Fig. 4 | Cell & Bioscience

Fig. 4

From: Extracellular matrix remodelling and stiffening contributes to tumorigenesis of salivary carcinoma ex pleomorphic adenoma——A study based on patient-derived organoids

Fig. 4

Heatmap and volcano plot of DEGs in PA and CXPA organoids and the top-ranked GO terms and KEGG pathways. (a) The heatmap (yellow, up-regulated; blue, downregulated). (b) The volcano plot (p-value < 0.05, |log2FC|>1; red and blue squares). The p-value was adjusted using the Benjamini-Hochberg method. Bubble plots displaying the top 30 GO terms in 3403 up-regulated DEGs (c) and 1636 downregulated DEGs (d). Bubble plots displaying the top 20 enriched KEGG pathways in 3403 up-regulated DEGs (e) and 1636 downregulated DEGs (f)

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Cell & Bioscience

ISSN: 2045-3701

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