The emerging studies on mesenchymal progenitors in the long bone

Cell & Bioscience

Table 1 Characterization of embryonic and fetal derived mesenchymal progenitors

Development stage	Location	Cell name in reference	Marker	References
Mesenchymal condensation	Limb bud	Limb mesenchymal cells	Prx1⁺	[12]
Mesenchymal condensation	Limb bud	Musculoskeletal precursors	Hoxd13⁺/Tbx13⁺	[13]
Mesenchymal condensation	Limb bud	Osteo-chondrogenic progenitors	PRRX1⁺ PDGFRA⁺SOX9^low	[14]
Cartilage template	The core of the limb bud mesenchyme		Sox9⁺	[15]
Cartilage template/POC formation	The growth cartilage and perichondrium		Col2⁺	[18]
Cartilage template/POC formation	The growth cartilage and perichondrium		Sp7⁺	[18]
Perichondrium formation/POC formation	The innermost part of the perichondrium		Nes⁺	[21]
Perichondrium formation	The outer layer of perichondrium		Hes1⁺	[22]
Perichondrium formation	The outer layer of perichondrium		Dlx5⁺	[22]
Perichondrium formation	Perichondrium		Pthlh⁺	[23]
Fetal growth plate development	The second half of pre-hypertrophic zone and first half of hypertrophic zone in the fetal growth plate	Human skeletal stem cells	PDPN⁺CD146⁻ CD73⁺CD164⁺	[5]
Fetal growth plate development	Chondro-osseous junction		Col10a1⁺	[25]

ISSN: 2045-3701