Fig. 4
![Fig. 4](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13578-022-00931-2/MediaObjects/13578_2022_931_Fig4_HTML.png)
Activation of Piezo1 by Yoda1 and MS induce Ptgs2 expression. A and B Heatmap and volcano plot of the DEGs from the RNA-seq assay with or without Yoda1 (20 µM) treatment (n = 3). C Gene Set Enrichment Analysis of the DEGs. D and E Heatmap D and Volcano plot E of the DEGs from the RNA-seq assay with or without MS (20 dyn/cm2) in As4.1 cells (n = 3). F Venn diagram showing numbers of the overlapped DEGs between Yoda1 and MS groups