Table 1 The summary of cellular localization of SARS-CoV-2 proteins
SARS-CoV-2 Protein | Confirmed subcellular localization by confocal microscopy |
|---|---|
Nsp1 | cytosol, perinuclear region |
Nsp2 | cytosol |
Nsp3 | membrane of vesicles, plasma membrane, not ER |
Nsp6 | ER, perinuclear region |
Orf3a | Golgi, weakly at ER, plasma membrane, lumen of vesicles |
Orf3b | cytosol, lumen of vesicles |
Orf6 | ER, membrane of vesicles (autophagosome, lysosome) |
Orf7a | mostly at Golgi, weekly at ER and mitochondria |
Orf7b | ER |
Orf8 | ER |
Orf9b | cytosol, plasma membrane |
Orf10 | cytosol, plasma membrane, perinuclear region |