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Fig. 3 | Cell & Bioscience

Fig. 3

From: Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells

Fig. 3

Pseudotime analysis characterizes expression changes throughout hESCs-derived LSCs differentiation. a, b UMAP visualizing developmental trajectories of cells for each cluster (a) and pseudotime assigned to each cell (b). c Spline plots showing expression changes of expression for the four candidate LSC marker genes, ABCG2, KRT14, KRT19, and TP63, over hESC-derived LSCs differentiation pseudotime. d, e Spline plots representing changes of expression for TFs upregulated upon differentiation and continually highly expressed (d), and upregulated in certain period (e) over hESC-derived LSCs pseudotime. f Spline plotts representing changes of expression for cell cycle related genes over hESC-derived LSCs pseudotime

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Cell & Bioscience

ISSN: 2045-3701

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