Fig. 3

Comparison of p53^−/− murine and human primary liver neoplasms according to WHO criteria for human. Representative images of typical (a mouse no. 263), intermediated-cell (c mouse no. 271), and cholangiolocellular foci (e mouse no. 266) in murine tumors based on the WHO criteria descriptions are presented side by side with images of corresponding intermediate area from typical subtype (b patient no. 1), intermediate-cell subtype (d patient no. 5), and cholangiolocellular foci (f patient no. 3) of human combined hepatocellular-cholangiocarcinoma with stem cell features