Fig. 4
From: XPD suppresses cell proliferation and migration via miR-29a-3p-Mdm2/PDGF-B axis in HCC
MiR-29a-3p directly targets Mdm2 or PDGF-B. a Schematic of the putative miR-29a-3p target site in Mdm2 3′-UTR and the seven mutated nucleotides are in lines. b Schematic of the putative miR-29a-3p target site in PDGF-B 3′-UTR and the seven mutated nucleotides are in lines. c QRT-PCR analysis of miR-29a-3p in SMMC7721 cells transfected with miR-29a-3p mimic or mimic NC. d Western blotting analysis of Mdm2, PDGF-B and P53 in SMMC7721 cells transfected with miR-29a-3p mimic or mimic NC. e QRT-PCR analysis of miR-29a-3p in Hep3B cells transfected with miR-29a-3p inhibitor or inhibitor NC. f Western blotting analysis of Mdm2, PDGF-B and P53 in Hep3B cells transfected with miR-29a-3p inhibitor or inhibitor NC. (*P < 0.05, vs. mimic NC; #P < 0.05, vs. inhibitor NC)