Fig. 7

Notch-1 silencing abolished the protection effect of EPCs on lung injury induced by PQ in vivo. C57BL/6J mice were randomly divided into four groups (n = 10 per group), the PQ group; the PQ + EPCs group; the EPCs group; the PQ + EPCs + si-control group; the PQ + EPCs + si-Notch-1 group. a The lung W/D ratio and b lung injury score of the mice were detected. c The expressions of Notch-1, Nrf2, Hmox1 and Txnrd1 protein in lung tissues were detected using western blot. The representing section images of the injured lung tissues are shown in (d). **P < 0.01 vs. PQ; ^##P < 0.01 vs. PQ + EPCs + si-control