Fig. 4

a Tumors dissected from the sacrificed nude mice. b, c The mice were injected with siRNA-Invivofectamine 2.0 complexes (100 μl of 0.5 mg/ml relative to siRNA) directly into xenograft tumors as previously described at 14, 17, 20 days. The tumor weight and volume were measured and compared at 8, 11, 14, 17, 20 and 23 days. d Body weights were monitored daily