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Table 6 Top networks analyzed by IPA

From: Epigenetic alterations in TRAMP mice: epigenome DNA methylation profiling using MeDIP-seq

Rank

Top diseases and functions

Score

1

Tissue morphology, embryonic development, organ development

38

2

Cell-to-cell signaling and interaction, cell signaling, cellular function and maintenance

38

3

Cell death and survival, cancer, cell morphology

37

4

Cancer, gastrointestinal disease, cell death and survival

35

5

Cancer, carbohydrate metabolism, small molecule biochemistry

33

6

Cancer, cell death and survival, cellular response to therapeutics

33

7

Lymphoid tissue structure and development, organ morphology, organismal development

30

8

Cancer, gastrointestinal disease, post-translational modification

29

9

Cancer, dermatological diseases and conditions, gastrointestinal disease

29

10

Cell morphology, digestive system development and function, nervous system development and function

28

11

Cancer, gastrointestinal disease, cell death and survival

26

12

Cancer, drug metabolism, energy production

26

13

Cell-to-cell signaling and interaction, nervous system development and function, cellular development

26

14

Cellular movement, cellular development, skeletal and muscular system development and function

24

15

Cell death and survival, cancer, cellular development

24

16

Hereditary disorder, inflammatory response, metabolic Disease

22

17

Cell morphology, nervous system development and function, tissue morphology

21

18

Cancer, organismal injury and abnormalities, reproductive system disease

21

19

Cellular compromise, cancer, cardiovascular disease

19

20

Cell-to-cell signaling and interaction, tissue development, hematological system development and function

17

21

Cancer, organismal survival, organismal injury and abnormalities

16

22

Cellular assembly and organization, cellular function and maintenance, embryonic development

16

23

Cancer, organismal injury and abnormalities, reproductive system disease

16

24

Cell cycle, cellular movement, cancer

16

25

Cancer, developmental disorder, hereditary disorder

16