Fig. 1

Relative expression of mature hsa-let-7c-5p is regulated by EV71 infection. RD cells were infected with EV71 (MOI = 5) or not (mock infection) at the indicated time points. The expression of hsa-let-7c-5p was detected by stem-loop qRT-PCR and normalized to that of U6 snRNA. The data are presented as the mean ± SD from one representative experiment, and all results here and in all subsequent figures were replicated three times. Significant differences are indicated as follows: ***p < 0.001