Table 2 Top 30 genes down-regulated in ZIKV infected hNPCs compared to controls
Gene symbol | Entrez | Gene name | Log2 FC | p-value |
|---|---|---|---|---|
SIGLEC10 | 89790 | Sialic acid binding Ig-like lectin 10 | −3.60664 | 0.00005 |
CDC20B | 166979 | Cell division cycle 20 homolog B (S. cerevisiae) | −3.44083 | 0.0002 |
OR51E2 | 81285 | Olfactory receptor, family 51, subfamily E, member 2 | −3.05742 | 0.0001 |
CCNO | 10309 | Cyclin O | −3.00562 | 0.00005 |
SLCO4A1 | 28231 | Solute carrier organic anion transporter family, member 4A1 | −2.97508 | 0.0229 |
SGPP2 | 130367 | Sphingosine-1-phosphate phosphatase 2 | −2.69025 | 0.00035 |
RRM2 | 6241 | Ribonucleotide reductase M2 | −2.63783 | 0.00005 |
SFXN2 | 118980 | Sideroflexin 2 | −2.61672 | 0.00005 |
COLEC12 | 81035 | Collectin sub-family member 12 | −2.60458 | 0.00005 |
CHRNA1 | 1134 | Cholinergic receptor, nicotinic, alpha 1 (muscle) | −2.5688 | 0.00005 |
PRR22 | 163154 | Proline rich 22 | −2.54683 | 0.00045 |
DHFR | 1719 | Dihydrofolate reductase | −2.53145 | 0.00005 |
MFI2 | 4241 | Antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 | −2.50748 | 0.00005 |
MAPK15 | 225689 | Mitogen-activated protein kinase 15 | −2.46203 | 0.00005 |
C21orf58 | 54058 | Chromosome 21 open reading frame 58 | −2.39697 | 0.00005 |
SPEF1 | 25876 | Sperm flagellar 1 | −2.39565 | 0.00005 |
GHRL | 51738 | Ghrelin/obestatin prepropeptide | −2.35804 | 0.00805 |
ATG16L2 | 89849 | Autophagy related 16-like 2 (S. cerevisiae) | −2.34225 | 0.00005 |
CXCL14 | 9547 | Chemokine (C-X-C motif) ligand 14 | −2.33189 | 0.0015 |
SUSD2 | 56241 | Sushi domain containing 2 | −2.28898 | 0.00005 |
C6orf118 | 168090 | Chromosome 6 open reading frame 118 | −2.27987 | 0.00005 |
DLX6-AS1 | 285987 | DLX6 antisense RNA 1 | −2.26662 | 0.00005 |
ADAM28 | 10863 | ADAM metallopeptidase domain 28 | −2.25906 | 0.00005 |
NXPH2 | 11249 | Neurexophilin 2 | −2.22856 | 0.00005 |
AQP7P1 | 375719 | Aquaporin 7 pseudogene 1 | −2.2255 | 0.00005 |
EFCAB1 | 79645 | EF-hand calcium binding domain 1 | −2.19918 | 0.00005 |
WNT8B | 7479 | Wingless-type MMTV integration site family, member 8B | −2.19366 | 0.00005 |
PI15 | 51050 | Peptidase inhibitor 15 | −2.17615 | 0.00005 |
C1orf189 | 388701 | Chromosome 1 open reading frame 189 | −2.17531 | 0.01255 |
OLFML3 | 56944 | Olfactomedin-like 3 | −2.16835 | 0.0016 |