Cell line treated with H2O2 | Breakpoint | Remarks |
---|---|---|
HK1 | 245,590 | This chromosomal break falls within the AF9 region (at coordinates 245252–245612) that translocates with the MLL gene, resulted in MLL-AF9 fusion gene previously identified in ALL patient [GenBank:AM050804]. This breakpoint is three nucleotides different from a breakpoint (at coordinate 245593) reported in cultured normal blood cells treated with VP16 [35] |
245,677 | Â | |
245,823 | Â | |
245,850 | Â | |
245,892 | Â | |
246,110 | This breakpoint is four nucleotides different from a breakpoint (at coordinate 246114) reported in CEM cells treated with VP16 [35] | |
NP69 | 245,580 | This chromosomal break falls within the AF9 region (at coordinates 245252-245612) that translocates with the MLL gene, resulted in MLL-AF9 fusion gene previously identified in ALL patient [GenBank:AM050804] |
245,591 | This chromosomal break falls within the AF9 region (at coordinates 245252-245612) that translocates with the MLL gene, resulted in MLL-AF9 fusion gene previously identified in ALL patient [GenBank:AM050804]. This breakpoint is two nucleotides different from a breakpoint (at coordinate 245593) reported in cultured normal blood cells treated with VP16 [35] | |
245,613 | This breakpoint is 1 nucleotide different from a breakpoint (at coordinate 245612) identified in ALL patient [GenBank:AM050804] | |
245,659 | Â | |
245,703 | Â | |
245,796 | Â | |
245,944 | Â | |
246,000 | Â | |
246,057 | Â | |
246,113 | This breakpoint is one nucleotide different from a breakpoint (at coordinate 246114) reported in CEM cells treated with VP16 [35] |