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Table 1 Subcellular localization of HIV-1 proteins in mammalian and fission yeast cells

From: Molecular characterization of HIV-1 genome in fission yeast Schizosaccharomyces pombe

HIV-1 protein

Subcellular localization

Mammalian (references)

Fission yeast (this study)

Gag

Cytoplasmic membrane [51]

Cytoplasm

P17

Cytoplasm, membrane [52]

Cytoplasm

P24

Cytoplasmic membrane [53]

Nucleus and cell membrane

P7

Nucleus [54]

Nucleus

P6

Cytoplasmic membrane [55]

Throughout cella

P66

Cytoplasm [56]

Nuclear > cytoplasm

P51

Cytoplasm [56]

Cytoplasm

Integrase

Nucleus [57]

Nuclear > cytoplasm

Protease

No report found

Throughout cell

Gp120

No report found

Nuclear > cytoplasm

Gp41

No report found

Nuclear > cytoplasm

Vpr

Nucleic membrane [48]

Nucleus [58]

Vpu

Cytoplasm [59]

Cytoplasm

Vif

Nucleus [60]

Nucleus

Nef

Cytoplasm [61]

Throughout cella

Rev

Nucleus [62]

Nucleus

Tat

Nucleus [63]

Nucleus

  1. aDifferent subcellular localization pattern was observed.