Fig. 2

IL-22TG6 mice with high levels of circulating IL-22 (~600 pm/ml) are resistant to Con A-induced liver injury. WT and IL-22TG mice were injected with Con A (15 μg/g) for 24 h. a Serum ALT and AST levels were measured. b Representative H&E staining of liver tissues from mice treated with Con A for 24 h. Necrotic areas are indicated by dot circles. Values represent the mean ± SEM (n = 10-14). ***P < 0.001