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Table 7 Genes with decreased methylation that mapped to the Wnt/β-catenin pathway by IPA

From: Association of aberrant DNA methylation in Apcmin/+ mice with the epithelial-mesenchymal transition and Wnt/β-catenin pathways: genome-wide analysis using MeDIP-seq

Symbol

Gene name

log2 Fold Change

Location

Type(s)

ACVR1C

activin A receptor, type IC

−3.029

Plasma Membrane

kinase

GNAQ

guanine nucleotide binding protein (G protein), q polypeptide

−2.877

Plasma Membrane

enzyme

SOX13

SRY (sex determining region Y)-box 13

−2.877

Nucleus

transcription regulator

WIF1

WNT inhibitory factor 1

−2.877

Extracellular Space

other

CDH2

cadherin 2, type 1, N-cadherin (neuronal)

−2.708

Plasma Membrane

other

PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

−2.708

Cytoplasm

phosphatase

TGFB3

transforming growth factor, beta 3

−2.708

Extracellular Space

growth factor

PPP2R1B

protein phosphatase 2, regulatory subunit A, beta

−2.614

Plasma Membrane

phosphatase

CSNK1G3

casein kinase 1, gamma 3

−2.515

Cytoplasm

kinase

WNT11

wingless-type MMTV integration site family, member 11

−2.515

Extracellular Space

other

MARK2

MAP/microtubule affinity-regulating kinase 2

−2.292

Cytoplasm

kinase

WNT7A

wingless-type MMTV integration site family, member 7A

−2.292

Extracellular Space

cytokine

TCF7L1

transcription factor 7-like 1 (T-cell specific, HMG-box)

−2.167

Nucleus

transcription regulator

GJA1

gap junction protein, alpha 1, 43 kDa

−2.029

Plasma Membrane

transporter

PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

−2.029

Cytoplasm

phosphatase

PPP2R5A

protein phosphatase 2, regulatory subunit B’, alpha

−2.029

Cytoplasm

phosphatase

SFRP2

secreted frizzled-related protein 2

−2.029

Plasma Membrane

transmembrane receptor

SOX7

SRY (sex determining region Y)-box 7

−2.029

Nucleus

transcription regulator

SOX14

SRY (sex determining region Y)-box 14

−2.029

Nucleus

transcription regulator

TCF7L2

transcription factor 7-like 2 (T-cell specific, HMG-box)

−2.029

Nucleus

transcription regulator

TLE3

transducin-like enhancer of split 3

−2.029

Nucleus

other

WNT7B

wingless-type MMTV integration site family, member 7B

−2.029

Extracellular Space

other

WNT8B

wingless-type MMTV integration site family, member 8B

−2.029

Extracellular Space

other