Figure 4

CNV status in hESC lines. (A) The genome-wide CNV status of the random XCI hESC group (hES-25 P8, hES-26 P9 and hES-35 P9). (B) Average chromosomal distribution of 50 kb-3 MB size CNVs in the random XCI hESC group. (C) The genome-wide CNV status of the skewed XCI hESC group (hES-20 P9, hES-27 P10 and hES-39 P10). (D) Average chromosomal distribution of 50 kb-3 MB size CNVs in the skewed XCI hESC group. Blue marks indicate regions of copy number gains. Red marks indicate regions of copy number loss. Only CNVs with a size from 50 kb to 3 Mb are counted. RXCI, random X chromosome inactivation. SXCI, skewed X chromosome inactivation. Error bars represent SD. *P <0.05 versus RSCI group.