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Table 4 Univariate and multivariate analyses of various prognostic variables for overall survival in cohort 1

From: Overexpression of MACC1 and Its significance in human Breast Cancer Progression

 

Univariate analysis

Multivariate

 

P

Hazard ratio (95% CI)

P

Hazard ratio (95% CI)

Age

    

 ≤45

0.261

0.709 (0.389-1.291)

  

 >45

    

Menopausal status

0.589

1.223 (0.590-2.534)

  

Premenopausal

    

Postmenopausal

    

Tumor size (cm)

    

 ≤2

<0.001

5.930 (2.501-14.064)

0.027

2.833(1.125-7.132)

 >2

Lymph node status

    

 Negative

<0.001

5.581 (2.674-11.648)

0.001

3.836(1.786-8.239)

 Positive

ER

    

 Positive

0.11

0.458 (0.251-0.836)

0.044

0.534 (0.290-0.983)

 Negative

PR

    

 Positive

0.076

0.557 (0.292-1.064)

  

 Negative

ErbB-2

    

 Positive

0.837

1.101 (0.440-2.758)

  

 Negative

MACC1 expression

    

 Positive

0.001

3.682 (1.756-7.721)

0.010

2.730(1.277-5.839)

 Negative

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Cell & Bioscience

ISSN: 2045-3701

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