Figure 1
From: Wound trauma alters ionizing radiation dose assessment
Wounding enhanced the radiation-induced mortality, water intake, and body weight loss, and delayed wound healing rate. N = 20 mice per group. (A) Wounding reduced 30-day survival after irradiation. *P < 0.05 vs. sham, wound, and CI groups; **P < 0.05 vs. sham, wound, and RI groups. (B) Wounding and/or radiation increased water consumption during the first 6 d. Radiation alone inhibited water consumption, which returned to normal baseline at 7 d. *P < 0.05 vs. sham, wound, and CI groups; **P < 0.05 vs. sham, RI, and CI groups; ***P < 0.05 vs. sham, RI, and CI groups. (C) Wounding accelerated radiation-induced body weight loss. *P < 0.05 vs. sham, wound, and CI groups; **P < 0.05 vs. sham, wound, and RI groups. (D) Radiation delayed wound healing. *P < 0.05 vs. wound group. RI: Radiation injury at 9.75 Gy; CI: combined injury.